lgmartelotto.bsky.social
Sc/St-Omics pro-aficionado. Knowledge sharing is my thing. Views, opinions and comments are my own and do not represent those of my employer. Like/Share ≠ endorse Favorite quote: “Be curious, not judgmental”
👤 Joined on 02 December 2023
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@lgmartelotto.bsky.socialThis one's for the #scRNAseq lovers (or haters) everywhere @ozsinglecell.bsky.social @abacbs.bsky.social! The order of QC really matters, and most of us have been doing it wrong!!! 😱 Wonderful work by our PhD student @michellemeier.bsky.social in the @aliciao.bsky.social lab!
Show PostAnd thanks @lgmartelotto.bsky.social for already sharing it over on LinkedIn! 🙏 Also, a good one for all users of @10xgenomics.bsky.social to check out
Show PostIt's cool to see we aren't the only ones that think rationally designed probes + gapfilling is the future. Check out a corroborating workflow from @mgrillo.bsky.social, @lgmartelotto.bsky.social, Anna Nam, and colleagues: bsky.app/profile/mgri... 7/n
Show PostNew work from our @mgrillo.bsky.social with @lgmartelotto.bsky.social and others. Capture somatic mutations in single-cell assays via RNA-targeted gap filling. Check it out!
Show PostCapturing somatic mutations in single-cell probe-based assays (ie. 10X Flex) is a hard task, especially if you don't know *exactly* the mutations you want to capture, or if your target sequence is a mutational hotspot with many possible alternative alleles. Here's the way we pulled this off. Enjoy!
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