Riley Mangan

rimangan.bsky.social

29 August 2026 10:01

I'm very excited to share the preprint of the central project of my postdoc, titled "Sequence-to-function deep learning decodes human cis-regulatory evolution" available today on BioRxiv. Preprint: www.biorxiv.org/content/10.6...

Carl de Boer

carldeboer.bsky.social

29 May 2026 08:00

There is widespread homology across our genomes. How does this impact genomics models? Major update to our preprint! 🎉 We tested more models and more tasks; the overall findings were robust, but one conclusion on how future models should be trained differs⚠️ www.biorxiv.org/content/10.1...

Stein Aerts

steinaerts.bsky.social

16 April 2026 17:07

Very proud of this and so cool that enhancer-level models can predict the effect of genetic variation. There is so much personal variation in terms of gene regulation in the human brain, it is fantastic to uncover this thanks to technology (whole-genome sequencing and single-cell multiomics) and AI

Olga Sigalova

olgasigalova.bsky.social

16 April 2026 10:56

Happy to share our new preprint on non-coding genetic variation in the human brain and Parkinson's disease. Great team effort with @alexanrna.bsky.social, @juliedeman.bsky.social, Koen Theunis, and all co-authors, supervised by @steinaerts.bsky.social and @jdemeul.bsky.social. Thread below:

Alexandra P

alexanrna.bsky.social

16 April 2026 09:58

1/ 🧬 Happy to share our new preprint on modeling cis-regulatory variation in human brain enhancers across a large Parkinson’s disease cohort: www.biorxiv.org/content/10.6... Details in the thread below: