ssegurabayona.bsky.social
Postdoctoral researcher in the Boulton Lab 🧬 The Francis Crick Institute, London, UK▪️interest in genome stability, chromatin, cancer 🧫 👩🔬 EMBO and MSCA fellow
👤 Joined on 17 November 2024
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@ssegurabayona.bsky.socialOur latest work describing DDIAS as a new component of the TOPBP1-CIP2A pathway in mitosis and its requirement for brain development is now published. Fantastic collaboration with @fenaochs.bsky.social, @profstewartlab.bsky.social, Lars Allan Larsen, @tcr-miller.bsky.social, Zafar Iqbal & others
Show PostNew work from the lab! We report that DDIAS is a downstream effector of CIP2A-TOPBP1 in mitosis that suppresses ssDNA to preserve genome integrity. From the great @yiboxue.bsky.social and many collaborators! Free link: authors.elsevier.com/a/1nfiF3vVUP... Pay link: www.cell.com/molecular-ce...
Show PostBig congratulations Sandra and the whole team!!! Great story 👏🏼👏🏼👏🏼
Show PostOften mutated in cancer, the ATRX gene helps cells copy their DNA without damage. Crick scientists have uncovered new functions for this gene that might leave ATRX-deficient cancer cells vulnerable to potential treatments. https://bit.ly/4v7HTcW
Show PostExcited to share our latest paper! We found that large pieces of the human genome can transfer between cells upon direct contact, endowing recipient cells with heritable phenotypic changes. @cp-cell.bsky.social (1/7) www.cell.com/cell/fulltex...
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