Genes & Diseases Journal

genesndiseases.bsky.social

04 August 2026 14:48

Comprehensive analysis of #IKBKG mutations reveals domain-specific genotype–phenotype links across disorders like #Incontinentiapigmenti, with #ZincFinger variants driving severe #immunodeficiency and distinct clinical manifestations. #OpenAccess: doi.org/10.1016/j.ge...

Akis (Argyris) Papantonis

akispapantonis.bsky.social

29 July 2026 10:02

Our latest is now out in @nataging.nature.com giving reason to celebrate! Led by talented Spiros Palikyras, it improves our preprint (posted 2 years ago!) dissecting the mechanism and functional consequences of CTCF clustering upon senescence commitment of human cells. www.nature.com/articles/s43...

Takashi Fukaya

fukayalab.bsky.social

28 July 2026 13:54

New preprint from the lab! We identify the ZnF protein Mulberry as a condensation-dependent structural regulator of genome topology that organizes “multi-way regulatory hubs” in early Drosophila embryos. www.biorxiv.org/content/10.6...

Teif lab

teiflab.bsky.social

28 July 2026 13:41

Chen et al 2026. Genome-wide rotational and translational phasing of nucleosomes with human transcription factors www.cell.com/molecular-ce... ▶️ In vivo nucleosome phasing measured on the same TF-bound DNA molecule ▶️ Phasing around CTCF sites is DNA encoded ▶️ FoxA and NFIA phase adjacent nucleosomes

Danielle Bianchi

daaninthelab.bsky.social

28 July 2026 13:40

In today’s publication in Science we introduce Zincore: a novel protein of QRICH1 and SEPHS1 and functions as a transcriptional coregulator dedicated to zinc finger transcription factors. Here’s how we found it: 🧵 www.science.org/doi/10.1126/... 1/11