teiflab.bsky.social
Teif lab at the University of Essex. We work on gene regulation in chromatin and applications to liquid biopsies, using approaches of genomics, biophysics, bioinformatics & AI. Our focus is nucleosomics, TF binding, CTCF, cfDNA. https://generegulation.org
👤 Joined on 13 November 2023
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Funded PhD in my lab 🧬 Decoding DNA replication origins using genome language models (w/ Ke Li's group) — then engineering new ones. AI + nanopore sequencing + Biofoundry automation ⚙️ (w/ @cgrandel.bsky.social). We validate computationally AND experimentally. ⏰Deadline 30 Nov 2026. shorturl.at/6jYFP
Show PostHow do genes communicate across long stretches of DNA? Join @leonidmirny (MIT) as he explores how rare cohesin bridges formed during loop extrusion may bring enhancers and promoters together—and reveals a new way CTCF can control these interactions! nyulangone.zoom.us/webinar/regi... #chromatin2026
Show PostMy first solo review article is out! 🎉 Can KRAB-zinc finger genes and ERVs co-evolve not just in an antagonistic “arms race,” but also “arm-in-arm”? 🧬🤝🧬 Very excited to share this work and grateful to contribute to this TE-focused special issue @virusesmdpi.bsky.social! 😄 www.mdpi.com/4141652
Show PostEach human (resting CD4+ T) cell has about 2 meters of DNA crammed into the nucleus. Therefore, the challenge is not just storing DNA but folding it in a way that preserves function. rdcu.be/fsd7v
Show PostHow open is “open” chromatin? Our new Nature Genetics paper uses nucleosome-resolution modeling to reveal condensed euchromatin domains with short, accessible regulatory regions at the surface. www.nature.com/articles/s41...
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