gliperis.bsky.social

👤 Joined on 15 December 2025

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Q4-Which biomarkers, imaging approaches, or omics technologies could help identify impaired decidualization, abnormal implantation, or defective placentation in artificial cycles before clinical complications become evident? #ESHREjc

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29 May 2026 16:23

Indeed, CL vs. no CL in our study comparing endometrial preparation protocols using ovulatory cycles (whether true natural/modified natural) vs. AC, on the outcomes of the first embryo transfer (to avoid the bias of previous failed attempts). Significantly higher LBR in cycles using a CL. #ESHREjc

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However, wherever possible, it seems now clear that NC should be considered, regardless of recipient age. #ESHREjc

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Also, moving the needle on NC would almost surely mean an increase in FET. Unfortunately, going full FET in oocyte donation may come at a PR cost, given the proportion of cycles with vitrified oocytes #ESHREjc

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There lies the complexity! In oocyte donation cycles, AC is the answer to 2 main issues: 1) irregular/absent menstrual cycles and 2) logistical reasons / donor availability. AC should not be demonized given its role in facilitating access, sometimes as only treatment option. #ESHREjc

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