"As he lay in bed, Bond heard a noise - the sort that spelt danger. Silently, he reached across to the bedside table for his teeth." © Alan Coren

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New @nejm.org #ACC25 The global impact of 5 cardiovascular risk factors (BP, cholesterol, obesity, diabetes, smoking) on life expectancy in men and women www.nejm.org/doi/full/10.1056/NEJMoa2415879

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This is strangely compelling: how the makers of Thunderbirds used toys and plastic model kits to efficiently populate a world with futuristic vehicles. youtu.be/wlD912KKMhA?...

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Quite an essay on the basis of cancer entitled "The End of the Genetic Paradigm of Cancer" @plosbiology.org arguing against the primacy of somatic mutations (traditional model) and cells, invoking gene regulatory networks and tissue journals.plos.org/plosbiology/...

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Single-cell RNA sequencing of immune cells for over 1,000 people age 18-97 years. A clock of our immune system aging. Tells us about an individual's response to infection, vaccination, Long Covid. Towards an immunome. www.nature.com/articles/s43...

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