fiammasalerno.bsky.social
Molecular Immunologist || T & B cell enthusiast || RNA-binding protein lover Tenure-track group leader @LUMC Leiden
👤 Joined on 31 December 2024
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@fiammasalerno.bsky.social👇Super excited about this work. 👇 Our first proteome analysis of tumor-reactive T cells from non-small cell lung cancer lesions. We identify differentially expressed proteins that we would have missed with RNA-seq. We learned how CHD4 and FASN contribute to T cell differentiation and function.
Show PostPhilippe Bousso (1971–2026) @cp-immunity.bsky.social www.cell.com/immunity/ful...
Show PostExcited to share our new paper in @insight.jci.org How does genetic risk shape CD4 T cell recognition in inflammatory bowel disease? #IBD We linked HLA-DRB1 genotype to >3.1 million memory CD4+ TCRβ sequences in Crohn’s disease, ulcerative colitis and controls.
Show PostUp to a fantastic start! The EMBO Workshop on Pathogen Immunity and Signaling has now started in Leiden! Nearly 180 participants from 25 countries have joined at Naturalis Biodiversity Centre to discuss great science! #EMBOsignaling26
Show PostFinally out in @Cellcellpress! Proteins with long IDRs are prone to misfolding during protein synthesis. This is prevented by mRNA 3′UTRs that act as mRNA-based IDR chaperones. www.cell.com/cell/fulltex...
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