Evgeny Kvon

evgenykvon.bsky.social

27 August 2026 14:01

Breakthroughs like this rely on standing on the shoulders of giants. Beyond new DL models, this work was only possible thanks to high-quality epigenomic #ENCODE datasets and massive VISTA collection of validated enhancers built over 20+ years by @axelvisel.bsky.social, Pennacchio and Rubin labs.

Ethan Hollingsworth

ewholling.bsky.social

26 August 2026 10:49

Really fortunate to continue this collaboration with @shenzhichen1999.bsky.social and @alex-stark.bsky.social while back in medical school and scratch the research itch. Still can't believe the model achieved 15/15 target tissues!

Evgeny Kvon

evgenykvon.bsky.social

26 August 2026 09:25

First synthetic mouse enhancers active in defined embryonic tissues! Great collaboration led by @alex-stark.bsky.social lab now at @natgenet.nature.com

Shenzhi Chen

shenzhichen1999.bsky.social

25 August 2026 10:58

Excited to share our paper in @natgenet.nature.com on the de novo design of tissue-specific mammalian enhancers that function in vivo in mouse embryos. 🧬🐭 www.nature.com/articles/s41...

IMP

impvienna.bsky.social

25 August 2026 10:58

The IMP lab of Alexander Stark used AI to design enhancers—DNA switches controlling gene activity—for specific mouse tissues: the first from-scratch design in a mammal. News: imp.ac.at/news/article/ai-learns-to-write-code-that-activates-genes-in-mammals Paper: nature.com/articles/s41588-026-02729-1