Amy D Willis

amydwillis.bsky.social

20 October 2026 11:19

Love 🦤radEmu🦤? You'll love ☄️fastEmu☄️! Fantastic work by @steichman.bsky.social fastEmu replaces a computationally expensive piece of hypothesis testing in radEmu with a cheaper approximation. Especially beneficial for large datasets & complex designs! Software: statdivlab.github.io/fastEmu Enjoy!

PLOS Biology

plosbiology.org

19 October 2026 09:19

The ratio of nonsynonymous to synonymous DNA substitutions (dN/dS) encodes information about selection pressures. This study develops a model of dN/dS in recombining bacterial populations, offering insights on how horizontal gene transfer shapes the genome. 🧪 #AcademicSky #evolution plos.io/3Wcy9lT

Martin Steinegger 🇺🇦

martinsteinegger.bsky.social

15 October 2026 06:33

LoL-align is out in @natmethods.nature.com! It aligns protein structures without superposition. More sensitive than TM-align and DALI, producing better alignments 5–20× faster. Now available in Foldseek! 📄 www.nature.com/articles/s41... 💾 github.com/steineggerlab/foldseek 🌐 search.foldseek.com

Matt Olm

mattolm.bsky.social

13 October 2026 11:05

Introducing Microbiome Repo, a catalog of every public human gut metagenome (>500k samples) with metadata pulled straight from sequence archives, papers, and supplements! olmlab.github.io/microbiome_r... Published gut metagenomes? Search your name and see if it got your study! Feedback welcome

Jim Shaw

jimshaw.bsky.social

13 October 2026 08:18

Skani (github.com/bluenote-157...) is now v0.4.0! Big performance update: **~2.5x faster** and ~30-40% less RAM for average nucleotide identity (ANI) comparison of genomes. The database format has changed (breaks forward compatibility; watch out!).