Alexandra P

alexanrna.bsky.social

16 April 2026 11:02

1/ 🧬 Happy to share our new preprint on modeling cis-regulatory variation in human brain enhancers across a large Parkinson’s disease cohort: www.biorxiv.org/content/10.6... Details in the thread below:

Niklas Kempynck

niklaskemp.bsky.social

08 April 2026 07:27

CREsted is finally out! You can find the article, together with a summarizing Research Briefing, in thread. 🦎

VIB.AI

vibai.bsky.social

03 April 2026 11:36

The @steinaerts.bsky.social lab published CREsted, an end-to-end modeling framework to 🧬 Train sequence-based enhancer models on large sc datasets 🔍 Decode enhancer logic with nucleotide-level interpretability ⚙️ Design synthetic enhancers with cell-type specificity https://tinyurl.com/ypurmrw5

Niklas Kempynck

niklaskemp.bsky.social

10 February 2026 06:46

Big thanks to Nelson & Trygve for guiding me, and to all the other people in the group for the nice collab. Thanks to @steinaerts.bsky.social for supporting me on this endeavor and to @fwovlaanderen.bsky.social for funding it. Also, Pacific Northwest nature is quite insane 😁

Niklas Kempynck

niklaskemp.bsky.social

10 February 2026 06:46

Last summer I spent 4 months working at the @alleninstitute.org as a Visiting Scientist. Recently we released some preprints about the work we collaborated on, where from new multiome atlases of CNS regions we tried to decipher underlying enhancer logic with CREsted (among many other things). (1/n)