sobolevsky.bsky.social
👤 Joined on 01 December 2024
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@sobolevsky.bsky.socialHappy to share the study of the mechanism of TRPV3 activation by cannabidiol (CBD) and inhibition by 14-deoxy-11,12-didehydroandrographolide (DDA) that are predicted to bind to the vanilloid site. The work led by Alexander Kalinovskii. www.sciencedirect.com/science/arti...
Show PostThank you to everyone sharing in this moment! I’m so grateful to all my trainees & collaborators… dlab.stanford.edu/group-members (pic: Peter and I together in 2017) Reading for all those asking: for technical details: dlab.stanford.edu for everyone: deisseroth.org/projections
Show PostOfficially out in Nature Communications: Structural and functional regulation of GluA2 AMPA receptor by inhibitory auxiliary subunits GSG1L and TARP y5 and by epilepsy-associated disease mutations. www.nature.com/articles/s41...
Show Post@sobolevsky.bsky.social and authors report structural and functional regulation of GluA2 AMPA receptor by inhibitory auxiliary subunits GSG1L and TARP [gamma] 5 and by epilepsy-associated disease mutations
Show PostMillions of beating cilia keep airways clean. At the base of each is the transition zone (TZ), a gate that controls which proteins enter and leave. In our paper out today in Science, we used cryo-FIB-ET to image the TZ inside human airway cells www.science.org/doi/10.1126/...
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