Ross Chapman

rosschapmanlab.bsky.social

30 September 2026 19:18

Check out our latest, just out in @MolecularCell! We reveal how common, typically harmless forms of DNA damage synergise with DNA replication defects in ATM-deficient cells to drive tumour-specific responses to PARP inhibitors - We propose that a similar synergy may contribute to A-T pathogenesis.

Sarah Aitken

s-j-aitken.bsky.social

10 August 2026 10:22

🔬NEW PREPRINT🔬 Explainable machine learning relates histological to genomic pathology www.biorxiv.org/content/10.6... From John Connelly and Barbara Hernando @bhernando.bsky.social, co-led with Martin Taylor @mstaylor.bsky.social - along with others from #LCEConsortium #genomicPathology #ml #ai

Paul Flicek

paulflicek.bsky.social

27 July 2026 16:09

It's fantastic to see this finally published! Huge credit to @s-j-aitken.bsky.social and @mstaylor.bsky.social for their determination and creativity on this project, which went in many unexpected directions (with many people along for the ride) and way beyond the initial experimental questions

Sarah Aitken

s-j-aitken.bsky.social

27 July 2026 06:34

🧬NEW PAPER🧬 To what extent is cancer development deterministic? Does the germline genome affect that predictability? Find out in our #StrainDifferences paper @nature.com "Genetic background sets the trajectory of experimental cancer evolution" www.nature.com/articles/s41... 🧵[1/14]

Barbara Marte

barbmarte.bsky.social

22 July 2026 16:43

new out in Nature www.nature.com/articles/s41...