New paper: doi.org/10.1371/jour... Why do hypermutant cancers have atypical 'weaker' driver mutations? Modelling clonal dynamics, shows that accelerated mutation rates and biases explain this enrichment in MMRd/POLEd colorectal cancers, shifting expected genotypes.

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Inherited genetics don't just influence cancer risk, they shape how tumors evolve and respond to treatment. A Yale-led Nature study suggests genetic background plays a far larger role in cancer progression than previously understood.👇Read more here👇 news.yale.edu/2026/07/27/g...

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We’re pleased to announce Professor Mariam Jamal-Hanjani as our new Chief Clinician! 🎉 Mariam is Professor of Cancer Genomics and Metastasis at UCL Cancer Institute and has led on a number of our key research initiatives. Join us in welcoming her to the role! cruk.ink/4jGWABC

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You can now register for Mutations in time and space 2027 🎉🎉🎉🎉🎉🎉 www.embl.org/about/info/c... 🎉🎉🎉🎉🎉🎉 This time we're in beautiful Heidelberg over 15 - 18 June. Along with a stellar cast of invited speakers, there are a ton of slots for submitted abstracts. Please do come along and take part :-)

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Visibility in Academia, like in the world, is not fixed; it is produced. This piece “What Cell Biology Reveals About Academia” is a reminder that everyone has the potential to be either seen or unseen. sciencepolitics.org/2026/03/23/w...

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