Pliotas Group

Pliotas Group

pliotasgroup.bsky.social

Mechanosensitive channels & Membrane Proteins - Structural EPR Spectroscopy at The University of Manchester - DEER/PELDOR/PDS pliotasgroup.org

👤 Joined on 23 January 2025

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  • 23 Oca 2025, 16:23
    🎉 Bluesky'e katıldı - İlk kullanıcı adı: @pliotasgroup.bsky.social

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Bela Bode
22 March 2026 08:47

Just published: copper(II) binding to Human Serum Albumin. 1st structure including the ATCUN site that is square planar as expected. There are multiple copper(II) sites and EPR (including hyperfine and pulse dipolar) reveals occupation of multiple sites at low loading. doi.org/10.1039/D6QI...

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New pulse EPR study on the human membrane channel TRAAK enabled through heterologous spin labelling

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Bela Bode
21 March 2026 12:43

Work just published in @natcomms.nature.com rdcu.be/e9ieD demonstrating how pulse dipolar EPR can resolve different states of a human transporter in native membranes. EPR contributions by @ackermannkatrin.bsky.social @st-andrewschem.bsky.social

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Protein–polymer conjugates: how do we understand their structure & dynamics? 🔬Our new review highlights EPR spectroscopy+complementary techniques for insights in vitro & in cells. Read more 👇 www.sciencedirect.com/science/arti... #ProteinPolymerConjugates #EPR #Biomaterials #PolymerScience

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In our study in @natcomms.nature.com we used #EPR #DEER #PELDOR spectroscopy with single subunit heterologous spin labelling and monitored the entire cap conformational ensemble of the human mechanosensitive TRAAK channel and showed it adopts two states in membranes. www.nature.com/articles/s41...

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