manishbutte.bsky.social
Pediatric immunologist specializing in inborn errors of immunity, T cell Immunologist, E. Richard Stiehm Professor, UCLA Dept of Pediatrics, Microbiology / Immunology, and Human Genetics
👤 Joined on 02 September 2023
Followers
Following
Total Posts
@manishbutte.bsky.socialIRF4 p.T95R combined #immunodeficiency: Clinical features and transplant outcomes. New study from Mattison P. Stojcic, Stuart E. Turvey (@turveylab.bsky.social, BC Children's Hospital, Vancouver) and colleagues: rupress.org/jhi/article/... #InbornErrorsOfImmunity #ClinicalPhenotypes #HSCT
Show PostAI researchers warn technology 'months away' from being able to get reimbursement using Concur
Show PostBiallelic loss-of-function PTPN6 variants lead to inflammatory lung disease and hemolytic #anemia. New report from S. Farshid Moussavi-Harami, Marco Tartaglia, Clifford A. Lowell, Mark R. Looney, Alice Y. Chan (UCSF) and colleagues: rupress.org/jem/article/... #Autoimmunity #inflammation
Show Post#Leniolisib, a PI3Kδ inhibitor, improves the pathophysiology of APDS. In @jhumimmunity.org, Rao, Uzel @charlesuni.cuni.cz et al. demonstrate the safety and efficacy of leniolisib in patients with APDS ≥12 years of age receiving up to 7 years of treatment. rupress.org/jhi/article/...
Show PostNew JEM study @mengzelyu.bsky.social & Sonnenberg (doi.org/10.1084/jem....) reports a counterintuitive result: blocking B7 costimulation promotes, rather than suppresses, the microbiota-specific RORγt⁺ Foxp3⁺ Treg cells. From @cytokinesociety.bsky.social: signals.cytokinesociety.org/2026/10/06/l...
Show Post