angelotaglialatela.bsky.social
Research Scientist at Columbia University Irving Medical Center
👤 Joined on 13 February 2026
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@angelotaglialatela.bsky.socialOur manuscript on the dependency of ALT-positive tumors on the DNA translocase SMARCAL1 is finally out in @genesdev.bsky.social. Big thanks again to the Min, Lazzerini Denchi and @cejkalab.bsky.social labs! @angelotaglialatela.bsky.social genesdev.cshlp.org/content/earl...
Show PostHappy to share ProTiler-Mut, a computational framework that leverages CRISPR tiling screens to map protein mutation–phenotype relationships, developed by Wei He and @hanxu-mdacc.bsky.social in collaboration with @raphguerois.bsky.social and our group. authors.elsevier.com/c/1nKys_siQz...
Show PostWe uncovered synthetic lethal interactions between Fanconi anemia genes and GEN1, CIP2A, and RHNO1; the translesion polymerase REV1-Pol ζ and the MCM8/9-HROB DNA helicase; and the DNA translocase SMARCAL1 and the FANCM complex, as reported also by @durocher1.bsky.social and @jcornlab.bsky.social.
Show PostExcited to finally share our preprint on mapping the genetic interaction network of the DNA damage response with combinatorial knockout screens led by Sam Hayward, Alina Vaitsiankova, and Tomas Lama-Diaz! www.biorxiv.org/cgi/content/...
Show PostAre you ready for the Summer? Social DNAing is! Check out the 2026 Summer line-up! Please note one schedule change on June 4th, 2026. Please RT! Sign up at cancer.columbia.edu/research/pro...
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