albertociccia.bsky.social
Scientist at Columbia University interested in genome stability and genome editing | http://www.genetics.cumc.columbia.edu/profile/alberto-ciccia-phd https://www.ciccialab.com/
👤 Joined on 13 November 2024
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@albertociccia.bsky.socialWorking with a great team to organize @keystoneSymposia.bsky.social DNA Replication: Pathway Crosstalk Shaping Physiology and Disease, this April! Join us to explore emerging research in London! keysym.us/KSDNA27 #KSDNA27
Show PostUCSF’s Kevan Shokat, PhD, just won the $1M Stephenson Global Prize for research in pancreatic cancer. He cracked KRAS, a cancer driver long considered “undruggable.” Drugs built on his work now treat lung and pancreatic cancer. https://ow.ly/UYuY50ZRSXg
Show PostI love what he has been doing. Paper out this week even on how to increase drug efficacy by targeting two sites by molecules with linkers.
Show Post🧬🔬 Why are enhancers transcribed and how does that impact gene regulation? I’m really excited to share our new paper in @science.org showing that noncoding RNAs control the timing of gene activation in embryos. With Mike Levine #ScienceResearch @columbiamed.bsky.social A few highlights below... 🧵👇
Show PostThrilled to share a new important study from the lab, published today in @nature.com, showing how cohesin mediates efficient replication fork plasticity and stress response, using its loop extrusion activity to promote 3D contacts on replicating DNA: www.nature.com/articles/s41...
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