A 14-protein plasma signature predicts lung cancer risk >5 years prior to diagnosis, aiding prevention trials and enhancing outcomes—promising approach to reduce NNT. PMID:42242224, Cell 2026, @Cell https://www.cell.com/cell/fulltext/S0092-8674(26)00522-2 #Medsky #Pharmsky #RNA #ASHG #ESHG 🧪

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IMO the paper of the year in the gene regulation field - such a clean and clear study, showing how promoter-enhancer contacts mediate transcriptional activation. www.cell.com/cell/abstrac...

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LEAPER 3.0 leverages endogenous ADAR for precise RNA editing using engineered RNAs, improving efficiency with insights from AlphaFold 3. Stunning potential! PMID:42269608, Cell 2026, @Cell https://www.cell.com/cell/fulltext/S0092-8674(26)00514-3 #Medsky #Pharmsky #RNA #ASHG #ESHG 🧪

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Revamping rice with reprogrammed DELLA turnover improves yield & nitrogen-use efficiency. Boosts sustainability, retaining benefits of 1960s Green Revolution varieties! 🌾 PMID:42393083, Nat Commun 2026, @NatureComms https://doi.org/10.1038/s41467-026-75068-8 #Medsky #Pharmsky #RNA #ASHG #ESHG 🧪

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A library of ~12,000 viral ORFs from 513 species was developed to uncover viral regulators of cell growth, MHC class I, and interferon signaling. Key insights await! PMID:42392077, Cell 2026, @Cell https://www.cell.com/cell/fulltext/S0092-8674(26)00583-0 #Medsky #Pharmsky #RNA #ASHG #ESHG 🧪

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