thexavierlab.bsky.social

Genes to functions. Microbiome in health & disease. Computational biology. Chemical biology. Innate & adaptive immunity. http://broadinstitute.org/xavier-lab https://molbio.massgeneral.org/faculty/343

👤 Joined on 19 November 2024

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  • 19 Kas 2024, 21:50
    🎉 Bluesky'e katıldı - İlk kullanıcı adı: @thexavierlab.bsky.social

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Early-life interventions & airway microbiome Nasal microbial gene atlas in infants w/cystic fibrosis. Hypertonic saline inhalation reshapes microbiome, selects salt-tolerant H. influenzae & ⬆️transporters linked to antibiotic tolerance @thexavierlab.bsky.social www.cell.com/cell-host-mi...

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What the nose knows of cystic fibrosis microbes and hypertonic saline Bouzek Previews work by @thexavierlab.bsky.social presenting microbial gene atlas of nasopharyngeal swabs in infants w/cystic fibrosis & healthy controls & IDing impacts of clinical interventions www.cell.com/cell-host-mi...

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Fun collaboration with @thexavierlab.bsky.social and Ribbeck groups to figure out how this human lectin plays multiple roles in controlling the #microbiome: stabilizing the mucus barrier and reducing bacteria that breach it. news.mit.edu/2026/protein... #glycotime

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Newly uncovered pathway behind tissue scarring, or fibrosis, in inflammatory bowel disease suggests new treatment strategies for the dangerous condition.

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This is a massive team effort! 💪 Huge thanks to the donors and staff @finngen.bsky.social and Finnish Blood Service for sample collection, the KCO team @broadinstitute.org for multiome sequencing, @thexavierlab.bsky.social @dalygene.bsky.social for supervision, and the entire team for their help!

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