A human iPSC model of tauopathies engineered for 4R tau isoform expression endogenously develops late-stage neuronal tau pathology | Science Translational Medicine www.science.org/eprint/5H5YD...

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🧠Constitutive neuronal expression and disease-associated upregulation of #chitinases in #amyotrophiclateralsclerosis 🔗Read a summary of the study on our website: www.synergy-munich.de/news-events/...

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New paper out today at @natneuro.nature.com in collab. with DichgansLab @isd-research.bsky.social @lmumuenchen.bsky.social: We developed a fully #iPSC-derived human model of the #BBB #blood-brain-barrier and applied it to study neurovascular disease (NVD)! #OA PDF here: rdcu.be/eUIl3 Thread👇 1/10

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Excited to share that our study on the role of the liver in #CancerCachexia is out in Cell! 😀 🧬 We found that the liver plays an active role in driving weight loss in cancer through disruption of the circadian regulator REV-ERBα and secretion of catabolic hepatokines www.cell.com/cell/fulltex...

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A study led by Anna-Sophia Wahl (@isd-research.bsky.social) reveals that the survival of place cells with stable coding for spatial information can be a strong predictor of positive cognitive outcomes following a #stroke. 🔗Read a summary on our website: synergy-munich.de/news-events/...

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