francoisrousset.bsky.social
Principal Investigator | Microbial Molecular Genomics Lab | https://www.rousset-lab.com |International Center for Infectiology Research (CIRI) in Lyon 🇫🇷 Studying the molecular basis of phage-bacteria interactions.
👤 Joined on 11 November 2024
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@francoisrousset.bsky.socialExcited to share this one, led by Theo and my postdoc Bel! We uncover how RNase E generates pAgo guide RNAs and how SPARMA turns that recognition into defense. We solved the cryo-EM structures in the Bravo lab. Great collaboration with Swarts & Zaremba! 🧬 www.researchsquare.com/article/rs-1...
Show PostNew preprint from my Post-Doc in the Swarts lab How are the guide RNAs generated that direct prokaryotic Argonautes to invading DNA? This has been an open question for >10 years. Our new study reveals that the host housekeeping enzyme RNase E is responsible! A 🧵: 1/14
Show PostCompetition among viral elements for VIPR RNA-directed genome silencing https://www.biorxiv.org/content/10.64898/2026.10.15.759431v1
Show Post1/5 Telomerase has long been linked to chromosome maintenance in eukaryotes. Now, we show that telomerase-like activity is also present in bacteria, shedding new light on its ancient origins. Excited to share that our work on DRT10 is now out in @nature.com! www.nature.com/articles/s41...
Show PostHeads up! The Symposium on the Immune System of Bacteria 2027 is now open for registrations! 20-22nd July 2027, Churchill College, University of Cambridge, UK Places are limited, so register soon. Visit the website to see our fantastic line-up of speakers: sisb2027.info #phage
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