moritzbauer.bsky.social
Post-Doc @hubrechtinstitute.bsky.social @jopkind.bsky.social. PhD @crg.eu PayerLab. Epigenetics, the X and single-cell technologies.
👤 Joined on 28 November 2024
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@moritzbauer.bsky.socialIncredibly happy to share our paper online! 🎉 We show how oscillations in Notch signalling help control cell fate decisions in the intestine. We wrote a little summary together, posted by Ina ⬇️ So proud of our team and the work we have done together! It’s been a journey!
Show Post🎉 Our paper is out today in @science.org! How does the intestine maintain the right balance of cell types? We find that signalling rhythms matter! So proud of our three shared first authors, Sonja Weterings, @hiromuneeto.bsky.social & @jddeleede.bsky.social! 🔗 www.science.org/doi/10.1126/...
Show PostThe @sonnenlab.bsky.social discovered a functional role for oscillation frequencies in keeping the gut cells in balance. They experimentally changed the frequency of Hes1 oscillations in intestinal organoids and showed that this altered cell-type composition.https://www.hubrecht.eu/cells-got-rhythm/
Show PostVery excited to share Waldo: a genetic single-cell barcode that can be read out in both live-cell imaging and single-cell sequencing, so both measurements can be made for the same cells. ⬇️
Show PostDid you ever want to sequence that one interesting cell you observed in your microscopy experiment? We have a new pre-print out today that describes a genetic barcoding method, Waldo, to perform live-cell imaging and single-cell sequencing on the same single cells. www.biorxiv.org/content/10.6...
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