Kenneth Loi

kenjmloi.bsky.social

19 October 2026 16:56

Viruses have parasites too. Our new preprint shows how phages use VIPR to silence parasitic satellites, and how the satellites fight back with its own decoy VIPR RNAs that redirect VIPR to DNA REP elements in the host genome!! www.biorxiv.org/content/10.6...

Kaçar Lab at UW-Madison

kacarlab.bsky.social

19 October 2026 16:56

How does evolution add new functions to proteins that are billions of years old? Our new paper explores how an ancient, essential component of the translation machinery (initiation IF2) evolved new ways to help bacteria survive environmental stress. Out now! 🧬 www.nature.com/articles/s41...

Sorek Lab

soreklab.bsky.social

16 October 2026 15:46

Very nice discovery from the Jackson, Bravo and Basel labs. Cleaved tRNA ends, loaded with an amino acid, activate a form of bacterial immunity

Martin Steinegger 🇺🇦

martinsteinegger.bsky.social

14 October 2026 20:01

LoL-align is out in @natmethods.nature.com! It aligns protein structures without superposition. More sensitive than TM-align and DALI, producing better alignments 5–20× faster. Now available in Foldseek! 📄 www.nature.com/articles/s41... 💾 github.com/steineggerlab/foldseek 🌐 search.foldseek.com

pilarcossio.bsky.social

14 October 2026 19:07

1/5 Cryo-EM gives high-resolution RNA structures, but only when high Mg²⁺ freezes out their motion. At physiological conditions, RNAs are dynamic and 3D reconstruction fails. Can we still learn their folding equilibria? New preprint: yes, straight from the raw particle images👇