Despite substantial weight loss, most obesity drugs such as Wegovy and Mounjaro do not meaningfully improve quality of life and few show cardiovascular benefits at one year, finds a new study in The BMJ https://bit.ly/4gmXim6 Read the linked commentary https://bit.ly/4f67A7I

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Wow! 🆕🔥🔴Multicenter OL NI RCT Oral fosfomycin (3 g once daily) was noninferior to continued intravenous therapy with carbapenems or BLBLIs when used as oral transition therapy for complicated UTIs caused by ESBL-producing Enterobacterales #IDSky #utisky academic.oup.com/cid/article-...

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There hasn't previously been a treatment vs pancreatic cancer this successful. Striking improved (a doubling) survival results @nejm.org and @ascocancer.bsky.social published today with daraxonrasib, which also became available via an FDA-approved early access program nejm.org/doi/full/10....

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The clinician’s primary role is to co-create pertinent, meaningful care with patients, not to be a technical validator of AI outputs. Poorly implemented AI systems risk accelerating the industrialisation of medicine, dehumanising both patients and clinicians.

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Clinician-in-the-loop: a flawed model for the safe deployment of AI in healthcare. www.bmj.com/content/393/...

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