Our plus/minus cryo-tide CDK11-cyclin L-SAP30BP #cryoEM reconstructions are now publicly available: www.emdataresource.org/EMD-59987 www.emdataresource.org/EMD-59992

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New research reveals that 3' UTRs of >2,700 human mRNAs control protein activity by influencing folding of intrinsically disordered regions (IDRs), impacting JMJD3 function. PMID:42259285, Cell 2026, @Cell https://www.cell.com/cell/fulltext/S0092-8674(26)00576-3 #Medsky #Pharmsky #RNA #ASHG #ESHG 🧪

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Very happy to share that Robert Prevedel and I have been appointed to jointly lead the EMBL Imaging Centre! Excited to work with our fantastic team to build on the Centre’s strong foundations and keep pushing microscopy, technology development, imaging services and image analysis forward!

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Struggling to choose a pixel size for your cryo-ET acquisition? Worry not: super-resolution processing can take in situ subtomogram averaging beyond physical Nyquist! We reached 2.8 A loc-res of a ribosome dataset with 4.78 A physical Nyquist limit! Our new preprint 👇: doi.org/10.64898/202...

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Out now in @science.org In situ structure of the human ciliary transition zone links linker defects to primary ciliary dyskinesia | Science www.science.org/doi/10.1126/...

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