Excited to share this work from our group, together with the Jackson and Beisel labs! 🧬 We found that aminoacylated tRNA fragments can act as signals to activate bacterial immunity, boosting protection by Cas12a3. Very cool biology, and a great collaboration! www.biorxiv.org/content/10.6...

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Sugar Rush Peach (and mango) pepper hot sauce! 🌶️

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Very strong winds and some rain today = no ringing (but data entry, laundering the bird bags etc). However, Landsort at Öja, in the very southermost part of the Stockholm Archipelago, is a beautiful place.

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LoL-align is out in @natmethods.nature.com! It aligns protein structures without superposition. More sensitive than TM-align and DALI, producing better alignments 5–20× faster. Now available in Foldseek! 📄 www.nature.com/articles/s41... 💾 github.com/steineggerlab/foldseek 🌐 search.foldseek.com

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Heads up! The Symposium on the Immune System of Bacteria 2027 is now open for registrations! 20-22nd July 2027, Churchill College, University of Cambridge, UK Places are limited, so register soon. Visit the website to see our fantastic line-up of speakers: sisb2027.info #phage

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