apanagopoulos.bsky.social
Senior Researcher @UZH. Interested in Genome stability, Cellular heterogeneity & Imaging.
👤 Joined on 19 November 2024
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@apanagopoulos.bsky.socialHow long after a mutation does it take for a cell to progress to cancer? In Barrett’s oesophagus, we found that CNAs occurred decades prior to cancer diagnosis, and that their rate is more prognostic than CNA burden alone doi.org/10.64898/202... (1/6)
Show PostOur work out today in @nature.com ! Incredibly proud of this team effort 🧬
Show PostOur work out today in @nature.com! We identified a previously unknown function for WEE1 in cell cycle control that could explain some of the inhibitor side-effects. We found WEE1 inhibits APC/C(Cdh1) to promote S-phase and cell cycle entry. Inhibit Wee1 , block or impair cell cycle entry.
Show PostMy first solo review article is out! 🎉 Can KRAB-zinc finger genes and ERVs co-evolve not just in an antagonistic “arms race,” but also “arm-in-arm”? 🧬🤝🧬 Very excited to share this work and grateful to contribute to this TE-focused special issue @virusesmdpi.bsky.social! 😄 www.mdpi.com/4141652
Show Post📢 We are excited to announce our latest work on oocyte meiotic checkpoint signalling @crick.ac.uk Led by George Sioutas, the work allowed us to delineate the early steps of the checkpoint signalling program of pre- and postnatal oocytes 🐭🧬https://www.biorxiv.org/content/10.64898/2026.10.13.758765v2
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