Nature Structural & Molecular Biology

natsmb.nature.com

13 October 2026 19:39

New online: Structural basis of an endoplasmic reticulum EMC:Spf1 insertase–dislocase complex

Molecular Cell

cp-molcell.bsky.social

12 October 2026 22:22

Online Now: A CK2-β-TrCP kinase-E3 ubiquitin ligase cascade is a metabolic sensor regulating tryptophan 2,3-dioxygenase stability Online now:

Alina Thielen

alinathielen.bsky.social

12 October 2026 22:21

I am thrilled to share that my PhD work is now published online in Molecular Cell! 🎉 www.cell.com/molecular-ce... Have a look if you like to learn how the essential amino acid tryptophan directly controls the stability of its metabolic enzyme TDO2 besides its role as a substrate!

Lillie Bell

lilliebell.bsky.social

12 October 2026 15:28

Happy to share my PhD work on the regulatory mechanism of E3 ligase RNF213! RNF213 is not a monomer, but a dimer that switches between inhibited and activated states in an ATP-dependent manner. We tracked the activation mechanism and showed how disease mutations can destabilize the inhibited state.

Sara Šepić

sarasepic.bsky.social

16 September 2026 14:23

Excited to share our latest work on understanding CTLH-MKLN1 substrate recruitment. Stay tuned for the paper 🤗