Cancer Heterogeneity and Plasticity

chp-pivot.bsky.social

01 September 2026 23:51

Breast cancer subtypes harbor distinct tumor immune microenvironments: • HR+: relatively immune-cold • HER2+: mixed immune features • TNBC: highly immune-infiltrated, yet also enriched in immunosuppressive features 📊 Table 1 compares these subtype-specific TIME landscapes.

Cancer Heterogeneity and Plasticity

chp-pivot.bsky.social

01 September 2026 23:51

📘 CHP Archive Spotlight #18 Review (2026) | Das et al. 🏛️ UC Santa Cruz How does breast cancer evade immunity? HR+, HER2+ & TNBC have distinct immune ecosystems—yet converge on shared mechanisms of immune escape. 🔗 doi.org/10.47248/chp2603010001 #BreastCancer #CancerImmunology

Mike Feigin 🥯

mikefeigin.bsky.social

23 May 2026 05:14

🚨 New preprint from the Feigin Lab! 🚨 www.biorxiv.org/content/10.6... Opioids have profound effects on the pancreatic cancer microenvironment! An FDA-approved opioid antagonist that doesn't cross the blood brain barrier decreases tumor aggressiveness in a mouse model of pancreatic cancer!

Needhi Bhalla 💅🏽

needhibhalla.bsky.social

14 May 2026 03:55

“If students note that you are ‘arrogant’ (as in being knowledgeable in your field, as your Ph.D. might suggest), drink.”

Benoit Bruneau

benoitbruneau.bsky.social

14 May 2026 03:55

To commemorate the lab’s 25 th, lab gifted me a lovely photo montage (man I look young in the older ones) and an awesome personalized guitar strap!