chp-pivot.bsky.social
Cancer Heterogeneity and Plasticity (ISSN 2818-7792) is an international peer-reviewed Open Access journal published quarterly by Pivot Science Publications.
👤 Joined on 11 April 2025
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@chp-pivot.bsky.social📘 CHP Archive Spotlight #12 Original Research (2026) | Wu et al. YAP1 depletion in gastric cancer peritoneal metastases (GCPM) induces compensatory TAZ activation, sustaining tumor progression and metastasis. Reveals adaptive oncogenic signaling via the YAP1–TAZ axis www.pivotscipub.com/chp/3/1/0004
Show Post📢 Call for Papers — CHP Special Issue Cancer evolves. Tumors adapt. Resistance emerges. Therapies fail. 📘 Molecular Understanding & Therapeutic Targeting of Cancer Heterogeneity and Plasticity 💡 OA | No fees 📅 Apr 30, 2026 (priority; open after) 🔗 www.pivotscipub.com/chp #CancerResearch
Show Post📘 CHP Archive Spotlight #09 Review (2024) | Balk & Goodrich From development to cancer progression, phenotypic plasticity shapes cell fate. This review dissects the molecular drivers linking homeostasis to therapy resistance. 🔗 doi.org/10.47248/chp... #PhenotypicPlasticity #Epigenetics
Show PostKey open questions: • What distinguishes reversible plasticity from stable lineage change? • How do epigenetic modifiers sustain reprogrammed states? • Can plasticity be therapeutically targeted? Emerging technologies may finally resolve these questions.
Show Post📘 CHP Archive Spotlight #07 Review (2024) | Her et al. How do noncoding RNAs drive cancer plasticity? miRNAs, lncRNAs, circRNAs & tRNA fragments regulate stemness, EMT, epigenetics & therapy resistance — with emerging roles as biomarkers & targets. 🔗 doi.org/10.47248/chp... #ncRNA #CancerStemCells
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