Adam Auton

adamauton.bsky.social

18 September 2026 02:06

What can we learn about a single rare variant? Published today in Science: the 23andMe Research Institute and Dana-Farber studied the EGFR T790M in 10.1M 23andMe research participants. The variant has OR = 25.2 for lung cancer, rising to 61.7 in never-smokers(!). 🧵

Jonathan Frazer

jonnyfrazer.bsky.social

10 September 2026 11:20

Congratulations! Beautiful work. I know Mafalda and @m1quelag.bsky.social found it a pleasure to review.

Noah Whiteman

nkwhiteman.bsky.social

07 July 2026 14:55

This is great Yun!

Michael Landis

landismj.bsky.social

06 July 2026 19:14

I'm delighted to share I was granted tenure on July 1st :-)

Stephen Lu

matrixmaster.me

08 June 2026 17:14

Antibody LMs learn what looks antibody-like, but not how selection turns naive germline antibodies into strong binders. @aakarshv1.bsky.social and I are excited to share CoSiNE, a model that learns this germline-to-mature process for variant effect prediction and antibody design. (1/8)