maxmadern.bsky.social
PhD student in the Tanenbaum lab, Hubrecht institute
👤 Joined on 19 January 2025
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@maxmadern.bsky.socialVery excited to share Waldo: a genetic single-cell barcode that can be read out in both live-cell imaging and single-cell sequencing, so both measurements can be made for the same cells. ⬇️
Show PostA bacterial self-destruct mechanism has been repurposed as a potential therapy go.nature.com/4hcWYqg
Show PostHappy to share our preprint! Using massively parallel reporter assays, single-molecule imaging, deep learning and cryo-EM, we decode the sequence requirements for translation initiation and describe the “extended translation initiation sequence” (eTIS) that modulates start codon recognition. 🧵👇
Show PostNew #preprint 😍‼️ led by 2 incredible postdocs @ninizhani.bsky.social & Ranj Papareddy: transforming #UFMylation from a local ribosome rescue pathway to systems level regulator of mRNA splicing www.biorxiv.org/content/10.6... A short 🧵
Show PostIn @science.org this week, thermospermine affects ribosome methylation, which in turn regulates translation of xylem development proteins www.science.org/doi/10.1126/... #plantscience
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