James Briscoe

jamesbriscoe.bsky.social

16 October 2026 08:55

New commentary from the lab - can we identify principles of transcriptional regulation & cis-regulatory element (CRE) control of gene expression? With @jcornwallscoones.bsky.social & @joadelas.bsky.social in @cp-molcell.bsky.social A thread 🧵 doi.org/10.1016/j.mo...

Jake Cornwall-Scoones

jcornwallscoones.bsky.social

16 October 2026 08:55

What’s inside the black box of cis-regulatory control? Our new review proposes a conceptual framework for understanding how regulatory inputs are integrated, linking molecular mechanisms to sequence constraints and quantitative rules, across scales.

Daniel Jost - Physical Biology of Chromatin group

djost-physbiol.bsky.social

15 October 2026 11:21

🚨 New preprint from the lab. SMC-mediated loop extrusion organizes the 3D genome. But how does this process—well characterized in vitro on naked DNA—navigate the crowded, nucleosome-dense chromatin landscape? Check the tweetorial below ⬇️ www.biorxiv.org/content/10.6...

FMI science

fmiscience.bsky.social

15 October 2026 11:21

Congrats to @anupamahl.bsky.social & Selma Dahmane on their @snsf.ch grants, totalling nearly CHF 2 million! Hemalatha's team will explore how metabolism shapes the fate of cancer-causing mutations in skin. Dahmane's group will investigate how immune cells detect Zika virus and trigger inflammation.

Pierre Haas

lepuslapis.bsky.social

05 October 2026 11:28

New #preprint: "Discontinuous buckling from cytoplasmic mechanics in vertex models of epithelia" arxiv.org/abs/2610.03239 More buckling from the #PhD work of @chandraniva.bsky.social.