Dr Kathleen Millen

neurodevkathy.bsky.social

30 April 2026 05:42

🤯🤯🤯 Prime editing + Gibson assembly =Prime Assembly at decent efficiency. Genome engineering technology is advancing so fast. Very exciting! Congratulations to all!

Morten

norholm.bsky.social

28 April 2026 12:25

In recombinant protein production, should we avoid rare codons—or rare tRNAs? In this new paper, I believe we make a compelling case that expressing rare tRNAs is a simple and efficient strategy to compensate for the use of rare codons. pubs.acs.org/doi/10.1021/...

Thomas Gorochowski

chofski.bsky.social

07 October 2025 08:33

🛠️New tool from the lab! #SHARK🦈: a new strain to support complex cloning of transient R6K expression plasmids – perfect for genome engineering. Work led by the talented Shivang Joshi and all strains and strain assembly tools enroute to Addgene. #synbio doi.org/10.1101/2025...

Dan Portik

dportik.bsky.social

01 October 2025 16:44

New pre-print from the Banfield lab, highlighting an interesting case of 1.5Mb megaplasmids found in human gut. Plasmid genomes were resolved using #PacBio HiFi sequencing with hifiasm-meta for #metagenome assembly. Host association was detected using epigenetic signals. doi.org/10.1101/2025...

Agathe couturier

agathe-couturier.bsky.social

18 September 2025 17:24

Exclusion systems, far from slowing down plasmid spread, are in fact essential to preserve host cell viability and thereby ensure the successful dissemination of conjugative plasmids and antibiotic resistance genes. @nfrk92.bsky.social @narjournal.bsky.social academic.oup.com/nar/article/...