Laboratory of Functional Viromics (LETKO)
fviromics.bsky.social
Dr. Michael Letko’s Laboratory of Functional Viromics | we study zoonotic potential of novel viruses. For more information, check out our website: https://labs.wsu.edu/lofv/
👤 Joined on 22 September 2023
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This is a decade of global teamwork: 137 researchers, 64 countries, samples gathered from the most remote corners of the planet🌍 Phase 1? Done ✅😍
Show PostWhy does all this matter beyond bats? 🦇🦇 Bats resist disease and live extraordinarily long for their size. This is the first robust framework to hunt for the genes 🧬 behind those traits - with potential relevance to human ageing and immunity 💡
Show Post🦇🧬We even reconstructed the genome of the ancestor of all living bats - a first glimpse of what the genome of the first flying mammal may have looked like ~65 million years ago
Show PostThis pattern is most consistent with extensive ancient gene flow between lineages early in bat evolution. A region of the X chromosome retained a signal of the true species relationships and was a 🔑 to resolving decades of conflicting hypothesis.
Show PostWhy had this been so hard to solve? Bat genomes contain a mosaic of evolutionary histories. Different regions, and even different chromosomes, support different relationships among the major lineages.
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