veeslerlab.bsky.social
Pathogen entry into cells, host immune responses & vaccine design: structural biology, protein design, virology & immunology @hhmi.bsky.social @uofwa.bsky.social
👤 Joined on 13 November 2024
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@veeslerlab.bsky.socialFolddisco is now published @natbiotech.nature.com. It’s a fast motif search for similar 3D DISCOntinuous residues like catalytic sites or zinc fingers across the entire protein universe. 📄 www.nature.com/articles/s41... 💾 folddisco.foldseek.com 🌐 https://search.foldseek.com/folddisco
Show Post7/7 Thanks to Lu Zhang, Nianzhen Chen, Georg Behrens, and Markus Hoffmann & team for the great collaboration. Preprint: “The conserved QTQTX motif in the SARS-CoV-2 spike protein is dispensable for cleavage and lung cell entry of the emerging variant BA.3.2” biorxiv.org/content/10.6...
Show PostFriday scripting - made a little CS-tools script to visualize the results of per-particle defocus refinement (here with the vault particle). The bottom panel is supposed to be a pseudo-tomo view looking in the plane of the ice layer; min_ice is the inferred ice thickness based on the mask extent
Show PostForgot to insert the tag for @veeslerlab.bsky.social on post #15.
Show PostWhen it rains myco publications in pours myco publications! Now out in PNAS tinyurl.com/2a6833n4 When @zestytoast.bsky.social accidentally isolated the long-chain acyl-CoA carboxylase, we quickly realized we were looking at a fascinating machine essential for building the mycobacterial membrane...
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