Boyi Guo (郭博逸)
@boyiguo.bsky.social did:plc:sjapbs2shtnjihxiaw45vh2r
Biomedical data scientist working at the intersection of machine learning 🤖, computational omics 🧬, and population health 👨👩👧👦 👨💻 Assistant professor @University of Utah 🔗 Personal website: https://boyi-guo.com/ 👤 Pronounce: he/him
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Boyi Guo (郭博逸) (@boyiguo.bsky.social) é um usuário do Bluesky desde 26 setembro 2023. Tem 170 seguidores, segue 123 contas e publicou 17 posts.
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And to @kr-maynard.bsky.social @stephaniehicks.bsky.social and Stephanie Page for leading this large team effort with me!
Ver postCongrats to co-first authors @shkwon-bcmbneuro.bsky.social and @boyiguo.bsky.social, and to @madhavitippani.bsky.social & @findycang.bsky.social who provided really unique analysis capabilities as well as the neuroanatomy/validation team led by @svitlanabach.bsky.social
Ver postIMO, have really important potential as resolution improves (now at 2uM scale!!) - to ask questions about how gene expression changes not only within defined spatial domains, but also local to changes in biological features that are functionally linked to disease
Ver postI am particularly jived about integration of protein detection w/ the spatial tech to ask questions about gene expression in cellular microenvironments - here neurovascular niche, synaptic neuropil and perineuronal nets. While the analyses were limited w/ the v1 Visium resolution, these approaches,
Ver postVery excited to get to share culmination of this large-scale project to understand spatial gene expression in schizophrenia. Really proud of the amazing team work here working out lots of roadblocks to deploy these spatial strategies and analysis methods at scale!
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