Boyi Guo (郭博逸)
boyiguo.bsky.social
Biomedical data scientist working at the intersection of machine learning 🤖, computational omics 🧬, and population health 👨👩👧👦 👨💻 Assistant professor @University of Utah 🔗 Personal website: https://boyi-guo.com/ 👤 Pronounce: he/him
👤 Joined on 26 September 2023
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- 26 Eyl 2023, 13:45
🎉 Bluesky'e katıldı - İlk kullanıcı adı:
@boyiguo.bsky.social - 13 Kas 2023, 01:55
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And to @kr-maynard.bsky.social @stephaniehicks.bsky.social and Stephanie Page for leading this large team effort with me!
Show PostCongrats to co-first authors @shkwon-bcmbneuro.bsky.social and @boyiguo.bsky.social, and to @madhavitippani.bsky.social & @findycang.bsky.social who provided really unique analysis capabilities as well as the neuroanatomy/validation team led by @svitlanabach.bsky.social
Show PostIMO, have really important potential as resolution improves (now at 2uM scale!!) - to ask questions about how gene expression changes not only within defined spatial domains, but also local to changes in biological features that are functionally linked to disease
Show PostI am particularly jived about integration of protein detection w/ the spatial tech to ask questions about gene expression in cellular microenvironments - here neurovascular niche, synaptic neuropil and perineuronal nets. While the analyses were limited w/ the v1 Visium resolution, these approaches,
Show PostVery excited to get to share culmination of this large-scale project to understand spatial gene expression in schizophrenia. Really proud of the amazing team work here working out lots of roadblocks to deploy these spatial strategies and analysis methods at scale!
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