immunoboys

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• Lennard Ostendorf@lostendorf.bsky.social03/02/2026 23:40

  Daratumumab in lupus 🦋 – results of our single-arm trial: 10 patients 8x daratumumab (1/week) at week 12: ☑️ reduced dsDNA antibodies ☑️ Median SLEDAI 12 > 4 ☑️ SRI-4 at 12 weeks 100% ☑️ immunology improved* out now at @nature.com Communications: www.nature.com/articles/s41... #medsky #nephsky 🧪 1/

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• bioRxiv Immunology@biorxiv-immuno.bsky.social14/12/2025 22:19

  Clinical development of gene edited tacrolimus-resistant Treg (FKBP12KO-Treg) to enable simultaneous immunosuppression and support of immune regulation https://www.biorxiv.org/content/10.64898/2025.12.10.693159v1

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• Lennard Ostendorf@lostendorf.bsky.social05/11/2025 18:24

  What mechanisms drive checkpoint inhibitor-associated interstitial nephritis (ICI-AIN)? In our preprint, we identify CD8 T cells as a central player, inducing a proinflammatory myeloid cell state by IFNg and structuring lymphoid aggregates by CXCL13. www.biorxiv.org/content/10.1... 1/n #Nephsky 🧪

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• Vijay Rathinam@vijayrathinam.bsky.social25/10/2025 00:46

  Thanks to Autoimmunity podcast @kevinbonham.bsky.social & @woodrufflab.bsky.social for discussing our glycoRNA paper w/ @raflynn5.bsky.social @vinnieviruses.bsky.social

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• JAMA@jama.com18/10/2025 15:17

  Syphilis is an infectious disease caused by Treponema pallidum, a gram-negative spirochete bacterium. This Review summarizes the epidemiology, diagnosis, treatment, and prevention of #syphilis. ja.ma/4qfKH6J

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