Lennard Ostendorf

lostendorf.bsky.social

03 February 2026 23:40

Daratumumab in lupus 🦋 – results of our single-arm trial: 10 patients 8x daratumumab (1/week) at week 12: ☑️ reduced dsDNA antibodies ☑️ Median SLEDAI 12 > 4 ☑️ SRI-4 at 12 weeks 100% ☑️ immunology improved* out now at @nature.com Communications: www.nature.com/articles/s41... #medsky #nephsky 🧪 1/

bioRxiv Immunology

biorxiv-immuno.bsky.social

14 December 2025 22:19

Clinical development of gene edited tacrolimus-resistant Treg (FKBP12KO-Treg) to enable simultaneous immunosuppression and support of immune regulation https://www.biorxiv.org/content/10.64898/2025.12.10.693159v1

Lennard Ostendorf

lostendorf.bsky.social

05 November 2025 18:24

What mechanisms drive checkpoint inhibitor-associated interstitial nephritis (ICI-AIN)? In our preprint, we identify CD8 T cells as a central player, inducing a proinflammatory myeloid cell state by IFNg and structuring lymphoid aggregates by CXCL13. www.biorxiv.org/content/10.1... 1/n #Nephsky 🧪

Vijay Rathinam

vijayrathinam.bsky.social

25 October 2025 00:46

Thanks to Autoimmunity podcast @kevinbonham.bsky.social & @woodrufflab.bsky.social for discussing our glycoRNA paper w/ @raflynn5.bsky.social @vinnieviruses.bsky.social

JAMA

jama.com

18 October 2025 15:17

Syphilis is an infectious disease caused by Treponema pallidum, a gram-negative spirochete bacterium. This Review summarizes the epidemiology, diagnosis, treatment, and prevention of #syphilis. ja.ma/4qfKH6J