Jesse Engreitz
@jengreitz.bsky.social did:plc:t2mrxdvr2ikozwnkm74xc7fz
Assistant Professor @ Stanford Genetics & BASE Initiative. Mapping the regulatory code of the human genome to understand heart development and disease. www.engreitzlab.org
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Résumé
Jesse Engreitz (@jengreitz.bsky.social) est sur Bluesky depuis le 21 novembre 2023. Le compte a 1 623 abonnés, suit 190 comptes et a publié 64 posts.
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It's been 30 years (!!!) since the conceptualization of GWAS. GWAS has driven tons of discoveries, but with recent experimental developments (CRISPR, single-cell omics), we thought it was time to think about how to drive the next 30 years of human genetics. doi.org/10.5281/zeno...
Voir le postHave you ever looked at a gene in IGV or a genome browser and wondered “What are all those (ATAC-seq/H3K27ac/CTCF ChIP-seq/…) peaks doing?” 🤔 I’m thrilled to share that we developed a new technology called Swap-seq to answer that exact question. Swap-seq: www.biorxiv.org/content/10.6...
Voir le postClaude made me an app to keep track of exploratory tasks on agentic projects (which quickly get out of control in the session). Point an agent at the workspace/prompt and it will populate tasks as it goes. Everything is recorded in markdowns/csvs. Code: github.com/sashagusev/f...
Voir le postHow do genetic variants affect secreted proteins? A new study introduces MultiSTEP, a scalable method for measuring variant effects in coagulation factor IX. The approach assessed >8,500 F9 missense variants and helped reclassify 63.1% of VUSs. pubmed.ncbi.nlm.nih.gov/40514537/
Voir le postFirst synthetic mouse enhancers active in defined embryonic tissues! Great collaboration led by @alex-stark.bsky.social lab now at @natgenet.nature.com
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