SP@RTE
@spartelab.bsky.social did:plc:6okyk6t26wkrrh337v3tnysc
#DNA repair, #Chromatin, #PARP, #Fluorescence #Microscopy and more in #Rennes
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SP@RTE (@spartelab.bsky.social) es un usuario de Bluesky que se unió el 18 noviembre 2024. Tiene 251 seguidores, sigue a 142 cuentas y ha publicado 9 posts.
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We are thrilled to share our latest publication in Cell Reports (Cell Press)! A huge thank you to everyone involved in this work! 📖 Read the full paper here: www.cell.com/cell-reports...
Ver postIn this study, we reveal that OGG1’s association with DNA during lesion searching involves local DNA distortion, promoting base unstacking. This process is tightly regulated by conserved amino acids encircling the double helix, ensuring stable binding without compromising rapid scanning.
Ver postI am happy to share our latest publication. In this work, we show that OGG1 association with DNA during lesion search involves local DNA distortion promoting base unstacking. This process is tightly controlled by conserved residues to ensure stable association without compromising fast scanning.
Ver postA coordinated haptic mechanism ensures efficient DNA sampling by the 8-oxoguanine glycosylase OGG1
Ver postVery happy to share our collaborative project on FAM118 proteins - noncanonical sirtuins that form filaments and process NAD in human and other vertebrate cells.
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