Jae Young Choi
@jychoi.bsky.social did:plc:r4zbfd3bhfjxk3hwwmlxqzzb
Assistant professor of evolutionary genomics at KU. Has a toddler 🙂🙃🙂🙃🇰🇷🇨🇦🇺🇲 https://jychoilab.github.io/
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Jae Young Choi (@jychoi.bsky.social) ist seit 27 Februar 2024 auf Bluesky. Das Konto hat 362 Follower, folgt 465 Konten und hat 46 Posts veröffentlicht.
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Just published in Science Advances: Mutations don't have the same cancer effect in driving development of melanoma at every age. Across 5,472 tumors, we find BRAF V600E loses selective advantage with age, while NRAS Q61 gains it. ♋ 🧪 www.science.org/doi/10.1126/...
Post anzeigenNew preprint 📄 Should long-read RNA-seq counts be normalized? We benchmarked 5 normalization methods × 5 quantifiers on PacBio and ONT, using spike-ins and matched Illumina as ground truth 🧵 www.biorxiv.org/content/10.6...
Post anzeigenWe got the cover! Way to go @jillmlove.bsky.social !!!!!
Post anzeigenPhylogenetic conservation scores have long been used to identify selection targets in the genome. With machine learning, they take a new form and will likely grow in popularity. @apragsdale.bsky.social and I investigate their relationship with mutation rates www.biorxiv.org/content/10.6...
Post anzeigenResearch is full of uncertainty, but every once in a while, nature works out exactly as you hypothesized. In 2019, while finishing my PhD, I pitched a bold idea in an email to @harmitmalik.bsky.social (below). Seven years later, it feels surreal to see that hypothesis become empirical reality. 🧵👇
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