Masashi Nomura
@masashi-nomura.bsky.social did:plc:mdb6y4r4ywll2r5caedix2ww
Physician scientist, Glioma single-cell genomics researcher, Neurosurgeon @Tokyo University, Postdoc in Suva lab @MGH/Broad
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Zusammenfassung
Masashi Nomura (@masashi-nomura.bsky.social) ist seit 8 April 2025 auf Bluesky. Das Konto hat 79 Follower, folgt 47 Konten und hat 31 Posts veröffentlicht.
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Precision medicine in high-grade gliomas? Using high-throughput drug screen in #NORLUX patient-derived organoids multi-omics and machine learning, we assessed pharmacogenomics: www.biorxiv.org/content/10.1... @fnr.lu, #precisionmedicine, #organoids, #drugscreen, #pharmacogenomics, #braintumors
Post anzeigenWe took a deep dive to understand the hereditary component of a family unduly touched by glioblastoma and uncovered a new pathogenic variant. This may reflect a paradigm: highly pathogenic and rare variants may be responsible for familial glioma risk. www.medrxiv.org/content/10.6...
Post anzeigen💫PUBLISHED @natgenet.nature.com 📰Longitudinal changes in DNA methylation in IDH-mutant glioma fuel disease progression through altered cell state differentiation. By @masashi-nomura.bsky.social, @landau.bsky.social, Mario L. Suvà and colleagues. ⬇️ www.nature.com/articles/s41...
Post anzeigenWonderful work by @masashi-nomura.bsky.social and team! This addresses an important question for the field about how DNA methylation loss influences malignant cell state changes in IDH-mutant glioma progression.
Post anzeigenIn our new collaborative paper on IDHmutant glioma with the Tirosh, Suva, Iavarone and Lasorella labs, we show how acquired genetic alterations converge with cell state changes and poor treatment responses. www.nature.com/articles/s41...
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