Anna Golebiewska

annagolebiewska.bsky.social

25 July 2026 14:39

Precision medicine in high-grade gliomas? Using high-throughput drug screen in #NORLUX patient-derived organoids multi-omics and machine learning, we assessed pharmacogenomics: www.biorxiv.org/content/10.1... @fnr.lu, #precisionmedicine, #organoids, #drugscreen, #pharmacogenomics, #braintumors

Roel Verhaak

roelverhaak.bsky.social

24 July 2026 10:34

We took a deep dive to understand the hereditary component of a family unduly touched by glioblastoma and uncovered a new pathogenic variant. This may reflect a paradigm: highly pathogenic and rare variants may be responsible for familial glioma risk. www.medrxiv.org/content/10.6...

Nature Genetics

natgenet.nature.com

16 July 2026 08:50

💫PUBLISHED @natgenet.nature.com 📰Longitudinal changes in DNA methylation in IDH-mutant glioma fuel disease progression through altered cell state differentiation. By @masashi-nomura.bsky.social, @landau.bsky.social, Mario L. Suvà and colleagues. ⬇️ www.nature.com/articles/s41...

Kevin Johnson

kevin-johnson.bsky.social

23 June 2026 13:39

Wonderful work by @masashi-nomura.bsky.social and team! This addresses an important question for the field about how DNA methylation loss influences malignant cell state changes in IDH-mutant glioma progression.

Roel Verhaak

roelverhaak.bsky.social

04 June 2026 06:52

In our new collaborative paper on IDHmutant glioma with the Tirosh, Suva, Iavarone and Lasorella labs, we show how acquired genetic alterations converge with cell state changes and poor treatment responses. www.nature.com/articles/s41...