New review from the Zhang Lab in @natmethods.nature.com led by @ammgest.bsky.social ! Explore recent advances in fluorescent proteins and biosensors, including improved photostability, high-throughput screening, quantitative imaging, and multiplexing.🔬 Check it out now!👇 doi.org/10.1038/s415...

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BindCraft2 v1.0.4 has been released: with significantly improved VHH, scFv, ARP, and induced fit targeting. WE also improved speed and code stability. Try your difficult campaigns again. Great work by @erikmaeots.bsky.social , Leonardo Tredese and @liza-ch.bsky.social

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A huge thank you also goes to all the collaborators in the labs of @tpatriarchi.bsky.social and Darren Gilmour: Musadiq, Yixing, and Jérôme!

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This one is special! First lab preprint: From when the competent bacteria were not competent and all the mammalian cells died all the way to a superb biosensor for ERK activity that works in neurons, spheroids, and zebrafish! And all of it by FLIM. Congrats Elias, Rohan, Dennis! tinyurl.com/389xzbtc

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Want to get clean calcium signals from tons of deep-brain neurons in freely moving animals? ​Check to this www.science.org/doi/10.1126/... @ScienceAdvances! We show how correcting GRIN lens aberrations transforms MINI2P performance, revealing sparse HD coding in sensory thalamus!

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