🧩 Together, these studies reinforce a clear effect on the gut–brain axis: metformin activates AMPK in enteroendocrine cells, restoring their ability to sense nutrient status and secrete hormones that shift metabolism in a positive direction. 🧪

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Metformin doesn’t just lower glucose; it teaches your gut how to sense nutrients again. Two new papers show exactly how this works, and why it matters. 💊🧪💊 Broken down in this thread. #Longevity #Aging #Healthspan

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I just launched my new Substack, Translation. I'll use this space to break down the latest longevity research, infer trends across disparate studies, and to share real-world protocols and applications. Please subscribe and join the conversation! jonbrudvig.substack.com #longevity #healthspan

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Neue #DFG-Analyse zur Fächerbeteiligung Exzellenzclustern innerhalb der #ExStra: Data Story zeigt breite fachliche Beteiligung; 90 % aller an dt. Universitäten vertretenen Lehr-/Forschungsbereiche sind vertreten. Hohe Interdisziplinarität; KI ist zentrales Thema ➡️ fcld.ly/exstradatast...

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After a long absence from Twitter, I'm now on Bluesky. Looking forward to sharing thoughts, research, and rants about the lack of attention paid to water. Let's kick this off with a new paper alert. Please share widely. Title says it all. Please help me grow followers www.science.org/doi/10.1126/...

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