dr-assir.bsky.social
Clinician-Scientist interested in early human brain development and neurodevelopmental disorders | Stem cells | Microglia | Maternal inflammation | 3D tissue culture | Neuroimmunology | Extracellular matrix | University of Aberdeen, UK
👤 Joined on 25 November 2024
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@dr-assir.bsky.socialWhen a larval zebrafish twitches its tail, the vascular endothelium lights up with a calcium signal, mediated by Piezo1. We used to think mechanosensing in endothelial cells was about sensing blood flow, but at least in this case it's about sensing body motion.
Show PostHonored to have a photo on the cover of Current Biology!
Show PostNature research paper: Cytosolic acetyl-coenzyme A is a signalling metabolite to control mitophagy go.nature.com/4qS89HD
Show PostWork by the awesome team of Alexander, Fani and @krademaker.bsky.social Explore the data interactively (>10 million cells spatially mapped across the developing human brain): www.stageatlas.org
Show PostHere, we mapped the expression of 250 known autism susceptibility genes in >10 million cells across the developing human forebrain using Xenium spatial transcriptomics
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