cdeichhorn.bsky.social
Assistant Professor and leader of @eichhornlab @ UNL | structure/dynamics/function of RNA & RNPs | views my own (she/her)
👤 Joined on 09 October 2023
Followers
Following
Total Posts
@cdeichhorn.bsky.socialHow do researchers design an RNA in 3D when no accurate 3D prediction model exists? Eterna's collaboration with the @rdaslab.bsky.social at Stanford was able to design novel pseudoknots using a blend of secondary structure prediction and GenAI design methods. 🧪 #RNAsky
Show PostCheck it out - ACS Cent Sci invites submissions to our In Focus series that showcase how basic science can translate to real world applications, first published example on NMR axial.acs.org/multidiscipl...
Show PostExcited to share our newest work! We asked whether RNA molecules need to be in a specific place in the cell to do their job. We found that a single RNA must reach the midbody, the structure that pinches two dividing cells apart, for cell division to finish efficiently. 🧵⬇️
Show PostNew bioRxiv preprint from our lab: www.biorxiv.org/content/10.6...: RNA recognition by tandem RRM RBPs is governed by a finely balanced conformational equilibrium. Both weakening and strengthening transient interdomain coupling reduce RNA binding. #NMR #RNABiology #StructuralBiology #bioRxiv
Show PostRiboseek is a fast RNA/DNA search. More sensitive than nhmmer at 250x speed. Structure-aware realignment produces MSAs approaching rMSA quality. Plus 1.7M precomputed RNA MSAs, and an API to search your own 📄 www.biorxiv.org/content/10.6... 💾 github.com/steineggerla... 🌐 search.foldseek.com/riboseek
Show Post